João Pedro Bebiano Costa

Investigador(a)

João Pedro Bebiano Costa

Investigador(a)

Biografia

João Pedro Bebiano e Costa é Investigador Científico e Gestor de Tecnologia de Inovação no CBQF – Centro de Biotecnologia e Química Fina assim como docente de engenharia de tecidos e biofabricação na ESB – Escola Superior de Biotecnologia da Católica. Obteve o Doutoramento em Medicina Regenerativa, Engenharia de Tecidos e Células Estaminais pela Universidade do Minho, em Braga, em 2019. Em 2022 ampliou a sua experiência ao concluir um MBA em Administração Hospitalar e Gestão da Saúde pela Universidade de Nebrija, em Madrid. Atualmente desenvolve investigação na área da medicina regenerativa, engenharia de tecidos, biomateriais e biofabricação, com um foco específico nas tecnologias de impressão 3D para o desenvolvimento de implantes personalizados.

O seu empenho em avançar nestas áreas foi recentemente reconhecido através de um prestigioso contrato obtido no âmbito do Concurso Individual de Estímulo ao Emprego Científico pela Fundação para a Ciência e Tecnologia. Este projeto de investigação – MOTION: Multi-biofabrication Of paTient-specific tIssues fOr regeneration of kNee meniscos – de seis anos é dedicado ao desenvolvimento de estratégias pioneiras de biofabricação para tecidos ortopédicos, particularmente no contexto da regeneração do menisco do joelho. Publicou 30 artigos científicos, tem a autoria ou coautoria de 3 patentes internacionais e já apresentou várias palestras em congressos nacionais e internacionais.

Publicações

Artigo

Silk proteins for 3D bioprinting

Ana Leite Oliveira & João Pedro Bebiano Costa (with Anabela Veiga). 2027. Biomaterials Advances

Biotecnologia da Católica e Ordem dos Engenheiros celebram protocolo de colaboração

Dia Mundial da Alimentação: Inovar hoje para nutrir o amanhã

Percursos Profissionais 26/27: a Biotecnologia para além da sala de aula

João Pedro Bebiano Costa

João Pedro Bebiano Costa

Biografia

Silk proteins for 3D bioprinting

A single workflow for the decellularization and sterilization of pancreatic tissue through supercritical CO2 technology

Bio-mechano-compatible electrospun scaffold as external support to prevent autograft dilatation in the ross procedure

Coaxial 3D printing of core-shell inks

Coaxial 3D printing of core-shell inks

Coaxial 3D printing of core-shell inks

Engineering mechanically tunable hydrogels from supercritical CO2-processed decellularized meniscus extracellular matrix

Going green and mimetic

Going green and mimetic

Greener fabrication of a bioadhesive meniscus-derived hydrogel via supercritical CO2-assisted decellularization

Toward a greener approach for next-generation functional pancreatic ECM in diabetes treatment - SEMIT

Coaxial 3D printing

Detergent-free supercritical CO2–assisted protocol for the production of sustainable and highly preserved decellularized porcine meniscus for orthopedic applications

Detergent-free supercritical CO2–assisted protocol for the production of sustainable and highly preserved decellularized porcine meniscus for orthopedic applications

Development of a decellularized extracelular matrix from porcine aorta for heart valve applications in the Ross procedure

Toward a greener approach for next-generation functional pancreatic ECM in diabetes treatment

3D printed bioactive interference screw and PCL bio-filler for ligament fixation

Design and bioprinting of decellularized extracellular matrix-based bioinks for skin tissue engineering

Development of coaxial-printing of scaffolds for meniscus replacement

In-situ fibroin conformational change using a coaxial-printing strategy for knee meniscus replacement

In-situ silk fibroin conformational change using a coaxial-printing strategy for knee meniscus replacement

Memory-shape hydrogels

Molecules in Motion: Unravelling the Dynamics of Vascularization Control in Tissue Engineering.

Novel knee implant fixation technology

Off-the-shelf silk sericin

Sustainable highly stretchable and tough gelatin-alkali lignin hydrogels for scaffolding and 3D printing applications

TechMENI

TechMENI

Decellularized dermal matrices

Design and Bioprinting of Decellularized Extracellular Matrix-Based Bioinks for Skin Tissue Engineering

SKIN2SKIN

Synergistic Effect of Co‐Culturing Breast Cancer Cells and Fibroblasts in the Formation of Tumoroid Clusters and Design of In Vitro 3D Models for the Testing of Anticancer Agents

Tackling current production of HAp and HAp-driven biomaterials

Bioinspired Silk Fibroin-Based Composite Grafts as Bone Tunnel Fillers for Anterior Cruciate Ligament Reconstruction

3DICE coding matrix multidirectional macro-architecture modulates cell organization, shape, and co-cultures endothelization network

Carbon nanotube-reinforced cell-derived matrix-silk fibroin hierarchical scaffolds for bone tissue engineering applications

Deep Learning in Bioengineering and Biofabrication: A Powerful Technology Boosting Translation from Research to Clinics

Engineering bioinks for 3D bioprinting

Memory-shape hydrogels

Silk fibroin-based 3d in vitro breast cancer model for drug screening applications

Silk Fibroin-based 3D in vitro Breast Cancer Model for Drug Screening Applications

3D Bioprinted Highly Elastic Hybrid Constructs for Advanced Fibrocartilaginous Tissue Regeneration

Convection patterns gradients of non-living and living micro-entities in hydrogels

Hybrid 3D-printing bioinks help repair damaged knee cartilage

Hybrid fibrocartilage tissue bioprinted for regenerative knee cartilage treatment

Researchers 3D bioprint fibrocartilage

Scientists create hybrid tissue construct for cartilage regeneration

The CAM assay as a model to study the angiogenic potential of biomaterials

WFIRM Scientists Create Hybrid Tissue Construct for Cartilage Regeneration

Advanced engineering strategies for bioprinting of patient-specific cartilage tissues. PhD thesis on Tissue Engineering

Assessment of the keratin effect on the angiogenic response of chitosan membranes envisioning peripheral nerve regeneration

Engineering patient-specific bioprinted constructs for treatment of degenerated intervertebral disc

Enhanced biocatalytic sustainability of laccase by immobilization on functionalized carbon nanotubes/polysulfone membranes

Enhanced performance of chitosan/keratin membranes with potential application in peripheral nerve repair

Enzymatically Cross-Linked Silk Fibroin-Based Hierarchical Scaffolds for Osteochondral Regeneration

Evaluating the effect of elastin in the angiogenic response of silk fibroin 3D printed scaffolds

Evaluating the effect of elastin in the angiogenic response of silk fibroin 3d printed scaffolds

Evaluation of the Angiogenic Effect of Elastin Incorporation on Silk Fibroin 3D Printed Scaffolds

Evaluation of the angiogenic response of keratin-enriched chitosan membranes for peripheral nerve regeneration

Implantable silk hydrogel microfluidic platform, methods of production and uses thereof

Indirect Printed Patient-Specific Scaffolds with a Bioactive Bottom Layer for Meniscus

Indirect printing of hierarchical patient-specific scaffolds for meniscus tissue engineering

Novel Enzymatically Cross-linked Silk Fibroin Bioink for Bioprinting of Patient-Specific Memory-Shape Implants for Meniscus Regeneration

Novel enzymatically cross-linked silk fibroin bioink for bioprinting of patient-specific memory-shape implants for meniscus regeneration

Novel enzymatically cross-linked silk fibroin bioink for bioprinting of patient-specific memory-shape implants for meniscus regeneration.

3D Printing of Silk-Based Bioink for Fabrication of Patient-Specific Intervertebral Discs Implants.

Biopolymers and polymers in the search of alternative treatments for meniscal regeneration: State of the art and future trends

Bioresorbable Calcium Phosphates Nanocomposites for Tissue Engineering

Combinatory approach for developing silk fibroin scaffolds for cartilage regeneration

Convection as a driving mechanism for gradients formation in interfaced gels for 3-D tissue interfaces

Current advances in solid free-form techniques for osteochondral tissue engineering

Differentiation of osteoclast precursors on gellan gum-based spongy-like hydrogels for bone tissue engineering

Hierarchical bilayered silk fibroin scaffolds containing ZnSr-ß-TCP particles for osteochondral tissue regeneration

Immobilization of laccase over carbon nanotubes for biocatalysis applications.