The Board of the School of Biotechnology includes a Dean, Paula Castro, and four Associate Deans: Paula Teixeira (Teaching), Manuela Pintado (Research), Cristina L.M. Silva (Internationalization) and Ana Gomes (Partnerships).

Each study cycle has a coordinator:

First-Cycle Coordinator - Paula Teixeira
Second-Cycle coordinator - Ana Gomes
Third-Cycle coordinator - Cristina L.M. Silva

In addition, each undergraduate, post-graduate, and master´s degree has a specific coordinator:

Undergraduate degree in Bioengineering - Paula Teixeira & Pedro Rodrigues (co-coordinator).
Undergraduate degree in Microbiology - Freni Tavaria
Undergraduate degree in Nutritional Sciences - Marta Correia

Post-graduation in Food Safety - Paula Teixeira
Post-graduation in Oenology - José António Couto
Post-graduation in Food Innovation - Ana Gomes
Post-graduation in Nutrition and Aging - Ana Gomes and Elisabete Pinto
Post-graduation in Pediatric Nutrition - Elisabete Pinto, Ana Gomes and Carla Rêgo
Post-graduation in Data Science in Biomedicine - Pedro Rodrigues

Master in Biotechnology and Innovation - Ana Gomes
Master in Food Engineering - Cristina L.M. Silva
Master in Biomedical Engineering - Ana Oliveira
Master in Applied Microbiology - Célia Manaia
European Master BiFTec-FOOD4S - Rui Morais

PhD in Biotechnology - António Rangel
PhD in Food Science and Technology and Nutrition - Isabel Vasconcelos (local coordination at the ESB) and José Teixeira (global coordination at the University of Minho)

Other governing structures include the Scientific Council - headed by António Rangel - and the Pedagogical Council - headed by Alcina Bernardo.

The research center CBQF (Center for Biotechnology and Fine Chemistry) has its own board composed of Manuela Pintado (director), Marta Vasconcelos (scientific strategy and internationalization), António Rangel (external relations and postgraduate training), Freni Tavaria (infrastructure and scientific platforms) and João Cortez (funding and career development).