Researchers at the Centre for Biotechnology and Fine Chemistry, from the Faculty of Biotechnology of Universidade Católica Portuguesa, are developing an innovative injectable osteochondral solution based on two distinct materials. The work focuses on ensuring component compatibility, appropriate handling performance, and biological relevance for both cartilage and bone tissues. The HYBROS – Hybrid Osteochondral Scaffold project has now moved into the technical implementation and experimental phase, following its official launch.

One of the main objectives at this stage is the development of a simplified protocol with rapid gelation, enabling both materials to be integrated into a single, efficient workflow. This approach is essential to ensure process scalability and compatibility with future manufacturing stages and clinical translation.

The HYBROS project is the result of an international collaboration involving GreenBone Ortho (Italy), Stemmatters (Portugal) and the Smart BioMaterials Consortium (the Netherlands), with support from the VInnovate 2024 Call, an initiative of the Vanguard Initiative dedicated to accelerating translational research and development projects.

In Portugal, the participation of the Centre for Biotechnology and Fine Chemistry of from the Faculty of Biotechnology of Universidade Católica Portuguesa is co-funded by the Northern Regional Programme 2021–2027 (NORTE 2030), managed by the Northern Regional Coordination and Development Commission.