Please join us on February 28th starting at 14:00.
No need to register - just show up in EBI 023.
João Francisco Botelho is our guest speaker.
Bacterial genomes exhibit remarkable plasticity, with many species harboring both chromosomal and secondary replicons. While core genes - essential for bacterial survival - are traditionally thought to exist exclusively in either the chromosome or secondary replicons, our research has uncovered a fascinating phenomenon: the simultaneous presence of core genes in different replicons within the same genome. In this talk, I will present our research exploring the implications of this discovery through an integrative approach combining comparative genomics, phylogenetics, and computational biology. This work has potential implications for both fundamental bacterial genetics and applied fields such as antibiotic design and biotechnology applications, providing new perspectives on bacterial genome evolution and adaptation strategies.