Integrative Biology: From Omics to Genome Editing

5 ECTS / Semester / English

Objectives and competences

This discipline aims to introduce the principles and potential of multi-omics, genome editing and systems biology. As this is a core area in the context of the course, subject to continuous methodological development, the aim of the discipline is to show the principles, tools, terminology inherent in the subject and, above all, where to look for information and practical guidance.

Specific objectives:
Understand the principles and applications of multi-omics technologies.
Learn about computational and bioinformatics tools used for analyzing multi-omics data.
Explore systems biology approaches for modeling biological networks.
Gain proficiency in genome editing techniques and their applications.
Develop critical thinking skills for designing experiments and interpreting results in integrative biology.

 

Teaching Methodologies

Lectures on key concepts.
Invited lectures
Presentation of individual and group work proposals.
Critical discussion of a current article on various applications of gene editing
Guided group work.
Guided individual work.
Bioinformatics exercises using specialized software
Laboratory work
Proposal of a new research project involving gene editing and the use of multi-omics
online and offline
Tutorial support
Support on the electronic platform (Campus online)

 

Syllabus

The course overviews multi-omics data analysis, systems biology modeling, and genome editing technologies. Students will learn about methods, data analysis, computational modeling, as well as molecular techniques essential for understanding complex biological systems and engineering genomes. By the end of the course, students will have gained a comprehensive understanding of how multi-omics, systems biology, and genome editing converge to advance our understanding of biological systems and pave the way for innovative applications in medicine, biotechnology, and beyond.

Introduction to Omics Technologies and integrative biology
Multi-Omics Data Analysis
Systems Biology Approaches
Genome Editing Technologies
Integration of Omics and Genome Editing:
Ethical, Legal, and Social Implications

Faculty

Associate Professor
Célia Manaia has a background in Biochemistry and specialization in Microbiology. Her academic career includes a Bachelor and Doctoral degrees concluded at…
Assistant Professor
Marta Vasconcelos has a Degree in Biology from the University of Lisbon, and a PhD in Biotechnology (specialty in Biology) from Universidade Nova de Lisboa…